Landing a role on a hit TV show is a dream for many actors because it offers rare job security. But some grow restless and, after becoming famous, decide to leave. For some, like George Clooney leaving *ER*, it works out well. For others, it doesn’t, and many later regret leaving the show that made them famous.

Wil Wheaton (Star Trek: The Next Generation)

Wil Wheaton played Wesley Crusher during the first four seasons of *Star Trek: The Next Generation* before deciding to leave, hoping to move on to bigger opportunities in TV and film. Given that many fans found Crusher somewhat annoying (and an early example of a Gary Stu), it seemed like a risk-free decision. However, Wheaton’s career didn’t take off as planned. Now 49, he has since reflected, saying, “At first, I thought it was a smart career move… but I wasn’t prepared for how much I’d miss the people on set. After it ended, I just felt really ashamed of myself.”