You’ve probably seen, or at least heard of, TLC’s hit reality show called My 600 LB Life. If you haven’t, you should. The show, aptly titled, centers its focus on people struggling to lose weight. We aren’t talking shedding 10 or 20 lbs to fit into your “someday” outfits, either.

The people that appear on the shows are looking to lose hundreds of lbs. Most guests start out at 600 pounds or more when they are introduced to the now famous surgeon, Dr. Younan Nowzaradan. Based out of Houston, TX, the surgeon, who often goes by Dr. Now, is committed to helping people who fall under the category of “morbidly obese” to lose enough weight to get themselves healthy and change their lives for the better.

Dr. Now first tries to help get a patient’s weight down through strict diet, and depending on a patient’s commitment and progress, will also offer one of two different types of surgeries; gastric bypass or sleeve gastrectomy. Both procedures involve surgically removing portions of the stomach and sewing the remains into a much smaller pouch or sleeve-shaped stomach. While these procedures seem drastic (and they are), it is the last chance, Hail Mary, for patients on the show who face critical, life-threatening health conditions due directly to their obesity.

My 600 LB Life isn’t a show about fat shaming. It’s a show about educating the world on what people who fall into this category go through in life, how they got there, and the hope that remains for them to turn it all around for the better. We have picked 25 of the most dramatic images of body transformations from guests who have appeared on the show. Both their stories and their struggles are downright inspiring!